Sleep Problems in the Elderly
Most adults need about 8 hours of sleep at night to feel fully alert when they’re awake. This is usually true for people age 65 or older too. But as we get older, we might have more trouble sleeping. Many things can get in the way of sleeping well or sleeping long enough to be fully rested. <.....more>
Elderly persons typically have less total nighttime sleep and less time spent in the deeper stages of sleep.
Older adults might get sleepy earlier in the evening. Older
adults may have trouble falling asleep when they go to bed at night. They might
not stay asleep all night. They might wake up very early in the morning and not
be able to go back to sleep. These problems can make older people very sleepy in
A number of things can cause sleep problems. By the time an adult
is over 65 years old, his or her sleep-wake cycle doesn’t seem to work as well.
Some lifestyle habits (like drinking alcohol or caffeinated drinks, or smoking)
can cause sleep problems. Sleep problems may be caused by illness, by pain that
keeps a person from sleeping or by medicines that keep a person awake. People of
all ages can have a sleep disorder such as sleep apnea, restless legs syndrome
or periodic limb movement disorder.
People with sleep apnea usually snore very loudly. Then they stop breathing for 10 to 30 seconds during sleep. They start breathing again with a gasp. This can happen hundreds of times in a night. Every time this happens it causes the person to wake up a little bit. Sleep apnea can cause daytime sleepiness. It can also make high blood pressure and heart disease worse.
If you have sleep apnea and are overweight, it might help to lose weight. It will also help to sleep on your side, and to stop drinking alcohol or using sleep medicines. Many people with sleep apnea need to wear a nasal mask during the night to keep their airways open. The mask treatment is called “continuous positive airway pressure,” or CPAP. It helps you breathe normally during sleep. Surgery can help some people with sleep apnea. <.....more>
This is a “creepy-crawly” feeling, mostly in the legs. It makes you want to move your legs or even walk around. It may be worse in the evenings when your legs are at rest. It usually happens every night and may start after you get in bed. This feeling may keep you from falling asleep. Older adults are more likely to have this problem.
If you have restless legs syndrome, placing hot or cold packs on your legs or taking a hot or cold bath might help to reduce your symptoms. Some people find relaxation techniques helpful. You can also try massaging your legs, feet and toes before going to bed. Certain medicines may help people who have restless legs syndrome. Your doctor will decide if using medicine is the right treatment for you. <.....more>
What is periodic limb movement disorder?
A person with this disorder kicks one or both legs many times during sleep. Often the person doesn’t even know about the kicking unless a bed partner talks about it. It can get in the way of good sleep and cause daytime sleepiness. Some people with restless legs syndrome also have periodic limb movements during sleep. Medicine may help both of these problems. <.....more>
For optimal daytime alertness, humans require about eight hours of sleep per 24-hour period.
Refreshing sleep requires both sufficient total sleep time as well as sleep that is in synchrony with the individual's circadian rhythm.
Problems with sleep organization in elderly patients typically include difficulty falling asleep, less time spent in the deeper stages of sleep, early-morning awakening and less total sleep time.
Poor sleep habits such as irregular sleep-wake times and daytime napping may contribute to insomnia. Caffeine, alcohol and some medications can also interfere with sleep.
Primary sleep disorders are more common in the elderly than in younger persons.
Restless legs syndrome and periodic limb movement disorder can disrupt sleep and may respond to low doses of antiparkinsonian agents as well as other drugs.
Sleep apnea can lead to excessive daytime sleepiness.
Evaluation of sleep problems in the elderly includes careful screening for poor sleep habits and other factors that may be contributing to the sleep problem.
Complaints of sleep difficulty are common among the elderly. Typical symptoms of sleep problems in the elderly include difficulty falling asleep and maintaining sleep, early-morning awakening and excessive daytime sleepiness.
A variety of processes may interfere with sleep and wakefulness in the elderly. Among them are acute and chronic medical illnesses, medication effects, psychiatric disorders, primary sleep disorders, social changes, poor sleep habits and circadian rhythm shifts.
Sleep-wake problems may be compounded further by inappropriate treatment initiated by the patient, family members, physicians or other care providers.
The consequences of chronic sleep problems can be considerable. Loss of sleep or chronic use of sedating medications may lead to falls and accidents.
Sleep-disordered breathing may have serious cardiovascular, pulmonary and central nervous system effects. Evidence supports a strong association between sleep apnea and hypertension.
For all of these reasons, sleep problems in elderly patients should be properly evaluated and treated.
Two primary factors control the physiologic need for sleep:
Under normal conditions, the circadian rhythm promotes a daily cycle of nighttime sleep and daytime alertness. Also commonly experienced is the physiologic mid-afternoon dip in alertness, which can be conducive to napping. It is now well established that a person's circadian rhythm is strongly influenced by exposure to light.
Normal sleep progresses through a number of stages during each sleep period. Rapid-eye movement (REM) sleep encompasses 15 to 25 percent of the total amount of sleep and is associated with dreaming, as well as increased liability of heart rate, blood pressure and respiration.
Non-REM sleep is subdivided into four stages of increasing depth. The deepest non-REM sleep generally occurs in the early part of the night. Episodes of REM sleep occur at approximately 90-minute cycles, with the duration of each episode tending to increase throughout the night.
Several generalizations can be made regarding aging and sleep characteristics. Compared with younger persons, elderly persons tend to achieve less total nighttime sleep.
However, it cannot be assumed that elderly persons require less sleep. Elderly persons have more nighttime arousals and awakenings.
Increased daytime sleepiness may be the effect of such a pattern.
The deepest stages of non-REM sleep are frequently reduced or nonexistent in elderly persons; however, REM sleep tends to be preserved.
Another common age-associated sleep change relates to the circadian rhythm of the typical sleep period.
Although exceptions exist, elderly persons tend to go to sleep earlier in the evening and to awaken earlier in the morning.
Early-morning awakening is a common complaint in the elderly. Some people find it annoying to awaken spontaneously at 4:30 a.m. instead of at 6:30 a.m.
In these persons, if the onset of evening sleep is not correspondingly earlier, sleep deprivation and excessive daytime sleepiness may result.
Daytime napping may compound the problem by reducing the drive for sleep at the usual bedtime hour, resulting in delayed sleep onset and a further decrease in the duration of nighttime sleep.
Less common in elderly persons, but sometimes dramatic, is the development of a "night owl" pattern, with bedtime delayed until the early-morning hours.
This sleep-wake cycle may have been tolerated in the younger years during employment, when the cues of early-morning bright light were stronger and the regularity of sleep-wake hours was greater.
On retirement, however, these cues weaken, and the sleep-wake cycle may become delayed by several hours. These patients may complain of day-night reversal, where sleep does not begin until dawn and then continues until mid-afternoon.
It is important to keep multiple factors in mind when evaluating sleep complaints in elderly patients because a number of problems may contribute to poor sleep
Factors Contributing to Sleep Problems in the Elderly
REM=rapid eye movement.
Nighttime insomnia and excessive daytime sleepiness should not be viewed as isolated symptoms. It is important to obtain a complete sleep history that includes the entire 24-hour day to examine all of the factors that may influence sleep and wakefulness
Factors to Consider When Evaluating Sleep Problems in the Elderly
Asking the patient to keep a sleep log that covers all sleep over a period of several weeks may be helpful in establishing the patient's sleep patterns.
Treatment directed at correcting inappropriate sleep-wake timing or increasing the total sleep time if it is insufficient may produce considerable improvement of the patient's sleep problem or even completely resolve it.
A full investigation of a complaint of insufficient sleep or excessive daytime sleepiness includes consideration of other potential problems that contribute to disrupted sleep, such as poor sleep habits, medical illness, medications and psychiatric disorders.
Poor sleep habits are a very common cause of sleep disruption.
Irregular sleep-wake patterns related to lifestyle or work requirements can undermine the ability of the circadian system to effectively provide sleepiness and wakefulness at appropriate times.
Caffeine intake can continue to have alerting effects for many hours. Consumption of caffeine-containing beverages in the afternoon can impair nighttime sleep.
Alcohol consumption in the evening, while initially sedating, prevents deeper sleep and increases arousals during the latter part of the night.
Excessive wakeful time in bed may cause the patient to develop increased arousal that is reinforced nightly.
Acute and chronic medical illnesses, such as arthritis, prostatic hypertrophy and cardiovascular, gastrointestinal and pulmonary diseases, may precipitate sleep disruption.
Pain and discomfort may delay sleep onset and shorten the duration of sleep.
Deterioration of the sleep-wake cycle can accompany neurodegenerative disorders, particularly Alzheimer's disease.
Many medications can have stimulating effects and thereby cause sleep disruption.
Included among them are some antidepressants (particularly selective serotonin reuptake inhibitors), decongestants, bronchodilators, some antihypertensives and corticosteroids.
Predictably, nighttime use of diuretics can promote repeated awakening to go to the bathroom.
The potential sedating effects of medications (especially long-acting sedatives that are inappropriately used as sleep aids) should also be a consideration in patients who report excessive daytime sleepiness.
Distress from acute symptoms of a psychiatric disorder may promote disturbed sleep.
A classic example is insomnia in association with major depression.
The tendency toward increased arousals and early-morning awakening in an elderly person may be severely exacerbated in the presence of depression.
Also contributing to a deterioration in the quality of sleep are the psychologic manifestations of the assorted life changes that elderly persons often experience.
Significant factors include physical limitations, loss of loved ones and leaving a familiar home to live in a more supervised setting.
Primary Sleep Disorders
Several primary sleep disorders are associated with aging. Primary sleep disorders may delay sleep onset, cause multiple arousals and awakenings, and promote excessive daytime sleepiness.
Wandering behavior and confusional arousals may occur, especially in patients with dementing disorders.
In rare instances, behaviors emanating from sleep may result in serious injury to the patient or bed partner.
Restless legs syndrome is characterized by an intense discomfort, mostly in the legs, during the evening when the person is at rest.
It is an akathisia, often described as a "creepy-crawly" sensation. The patient notes a strong urge to keep moving the legs or to get up and walk around to relieve the discomfort.
Restless legs syndrome is often treated with low doses of antiparkinsonian agents.
Periodic limb movement disorder, another primary sleep disorder, may accompany restless legs syndrome or occur independently.
This idiopathic condition is characterized by episodes of stereotypic rhythmic movement, usually of the legs, although other muscle groups, including the arms, may be involved in severe cases.
The patient's bed partner typically perceives these episodes as kicks that occur in cycles of 20 to 40 seconds. Hundreds of limb movements may occur during a single night, but most of the time they do not awaken the affected person.
They may, however, produce many brief arousals that disrupt sleep organization and decrease the amount of time in the deeper stages of sleep. The delayed sleep onset related to restless legs syndrome and the sleep disruption from periodic limb movements cause daytime sleepiness.
Restless legs syndrome is primarily a clinical diagnosis.
Periodic limb movement disorder may be suspected based on information obtained from a bed partner.
Risk factors for these two disorders include increasing age, renal failure and iron deficiency (serum ferritin level less than 50 ng per mL).
Up to one third of elderly persons have measurable periodic leg movements during sleep; however, only relatively high rates of events and high percentages of associated arousal should be regarded as clinically significant.
The degree of distress reported by the patient should influence the treatment decision.
Soaking the legs and feet in a warm bath or engaging in regular exercise provides relief of restless legs syndrome in some patients.
The most appropriate initial pharmacologic treatment for both restless legs syndrome and periodic limb movement disorder is carbidopa-levodopa (Sinemet) and other dopaminergic agents.
Comorbid conditions such as a low iron level also may need to be corrected for an adequate response. Carbidopa-levodopa (in the 25- to 100-mg formulation) may be started in a dosage of one half tablet at bedtime. The dosage can be increased in increments of one half tablet every three or four days, to a maximum of two tablets per day.
As with the use of carbidopa-levodopa in the treatment of Parkinson's disease, the development of so-called augmentation, where the motor restlessness begins earlier in the evening or in the afternoon, is a potential problem with this agent.
Pergolide (Permax), starting at a very low dosage, such as 0.05 mg two hours before bedtime, and gradually increasing up to 0.5 mg, also has been used successfully in the treatment of restless legs syndrome and periodic limb movement disorder.
In some cases, a bedtime dose of a benzodiazepine or a low-potency opiate, such as codeine or oxycodone (Roxicodone), may be beneficial.
Other drugs tried in the treatment of restless legs syndrome include bromocriptine (Parlodel), carbamazepine (Tegretol), clonidine (Catapres) and clonazepam (Klonopin).
Sleep apnea commonly causes repeated episodes of brief arousal, of which the patient often is not aware, and may promote extended awakenings from sleep.
The patient may report insomnia but more commonly notes excessive daytime sleepiness. Hundreds of apneic events may occur during a night.
The frequent sleep interruptions, coupled with repeated drops in the blood oxygen saturation, may cause a marked decline in daytime alertness and performance. Sleep may intrude on daytime activities such as driving, with dangerous consequences.
The apneic events usually result from complete or partial occlusion of the airway (obstructive sleep apnea) or, less commonly, from a decrease in the respiratory drive (central sleep apnea).
Risk factors for sleep apnea include male sex and obesity (especially a heavy neck). Sleep apnea may be associated with hypothyroidism, neurodegenerative disorders and cardiovascular disorders.
The major clinical clue to sleep apnea is a history of loud, excessive snoring, punctuated by pauses that are followed by stuttered gasps for breath.
Observations by the patient's bed partner or another family member can provide the physician with crucial information.
Weight loss is frequently beneficial in overweight patients with sleep apnea. However, the mainstay of therapy is continuous positive airway pressure during sleep, which is accomplished by having the patient wear a tight-fitting nasal mask.
Surgical intervention often eliminates snoring but may not eliminate the apnea. Effective control of sleep apnea can produce more consolidated nighttime sleep and a dramatic improvement in daytime alertness and functioning.
The rare REM-behavior disorder occurs most commonly in elderly persons. Underlying this disorder is disinhibition of the process that normally prevents transmission of muscle activity during dreaming.
The patient may thrash about in bed, sometimes falling or leaping from the bed and incurring significant injury.
Treatment with bedtime doses of a long-acting benzodiazepine such as clonazepam often provides effective control of this disorder.
General Treatment Considerations
Because many factors influence the sleep-wake cycle, treatment must be individualized according to the patient's specific symptoms and findings from the patient's evaluation.
Several generalizations are possible, however. Implementation of good sleep habits and daily physical activity should help create an environment conducive to restorative sleep.
Even if poor sleep habits are not responsible for insomnia, elimination of such habits can minimize their perpetuating influence.
Many patients with insomnia have excessive anxiety deriving from their failed attempts to sleep and respond well to a behavioral approach.
If hyperarousal at bedtime has evolved, it might be useful for the patient to spend less time in bed trying to go to sleep. This may help decrease the patient's anxiety over not being able to fall asleep.
Patients may be advised to avoid going to bed until they feel as though they can easily fall asleep.
An extended wakeful time in bed (e.g., more than 30 minutes) should be avoided to minimize further reinforcement of hyperarousal.
In addition, patients should plan relaxing nighttime activities before bedtime.
Selected patients may benefit from temporary use of sleep-promoting medications.
Over-the-counter antihistamines should be used with caution in the elderly because of their relatively long duration of action and their anticholinergic effects, which may cause confusion, constipation and urinary retention.
Low dosages of sedating antidepressants are especially helpful in patients with depressive symptoms. Consideration must be given to the duration of the sedation and other potential side effects.
If hypnotic medications are considered, the first choice would be a short-acting benzodiazepine receptor agonist.
Generally, a low dosage and short-term use are recommended. Intermittent dosing has advantages. Occasional use minimizes potential withdrawal effects.
Patients may be given guidelines, such as the recommendation that a hypnotic agent be used no more than two nights a week. The availability of a sleep medication may be reassuring to the patient on particularly difficult nights. That reassurance will likely decrease the patient's distress on nights when no medication is used.
While potentially valuable in offering relief of insomnia, hypnotic agents should not be regarded as the ultimate solution to a sleep problem. They should be used under limited circumstances, following evaluation of the patient's symptoms and in the context of good sleep habits.
The above opinionated views and information serves to educated and informed consumer . The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. It should not replaced professional advise and consultation. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions
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